Dr. Caroline Chang (former veterinary resident, PSU) and Dr. Ya-Yun Cheng (post-doc) have a new publication out in Gynecologic Oncology entitled “GPX3 supports ovarian cancer tumor progression in vivo and promotes expression of GDF15″.

Paper Highlights:

• GPX3 knock-down abrogates intraperitoneal tumor development in a syngeneic IP xenograft model of ovarian cancer.
• GPX3 modulates pro-tumorigenic gene expression and regulates the TGF-β family member GDF15.
• GPX3 expression correlates with regulatory T-cell and macrophage signatures, and PD-L1 expression in ovarian cancer.

Read more here:
https://pubmed.ncbi.nlm.nih.gov/38342006/