It has been some time since we have updated the website, but here are some recent publications from the lab:

Post-doctoral fellow Dr. Ya-Yun Cheng published “Loss of Predicted Cell Adhesion Molecule MPZL3 Promotes EMT in Ovarian Cancer” in July in Cancer Research Communications. This work was started by former graduate student Dr. Beth Worley. Ya-Yun and Beth found that decreased expression of the predicted adhesion molecule MPZL3 is associated with low proliferation but increased metastatic potential in ovarian cancer cells.

Another collaborative study entitled “Mapping transcriptomic signatures downstream of mitochondrial superoxide dismutase SOD2 in OVCA433 multicellular aggregates” carried out by graduate students Priscilla Tang and Amal Elhaw (now both PhDs!) was recently published in Advances in Redox Research. This study continues our long-standing interest in understanding the role of SOD2 in tumor progression, and shows that SOD2 knock-down decreases pro-metastatic transcriptional pathways, and that SOD2-dependent transcriotinal signatures identified in multicellular aggregate culture condions more closely reflect gene expression profiles associated with SOD2 in patient tumors.